Drosophila

Evolutionary genetics of energetic performance

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Luke A. Hoekstra [PDF]

Department of Biology
Indiana University
1001 E. 3rd St.
Bloomington, IN 47405



Phone: (319) 331-0573

lhoekstr AT indiana DOT edu
http://www.bio.indiana.edu/~montoothlab/

Research interests

Evolutionary ecology, evolutionary physiology, phenotypic plasticity. To date, my research has used physiological tools and classical genetics to gain a better understanding of the complexity of stress resistant phenotypes. I seek to understand how organisms cope with environmental stress and what factors will limit the ability of species to cope with rising global temperatures. My current project asks: 1) Is there an adaptive metabolic rate?, 2) What are the limits of the plastic response to temperature?, 3) How do complex physiologies evolve?

Education

M.S. Biology, College of William and Mary, 2010 (Expected).
Research Advisor: Dr. George Gilchrist
B.S. Biology, University of Iowa, 2005.
Research Advisor: Dr. Bryant McAllister

Previous research experience

Research assistant

Dr. Leonid Moroz & Dr. Andreas Heyland
Friday Harbor Laboratories
April-June 2008
Designed and implemented a research project to describe the behavior, physiology and neuroanatomy of the marine invertebrate Leptosynapta clarki. The results provide some of the first evidence of classical neural structures in an adult echinoderm nervous system and present a unique opportunity to connect echinoderm form to function.

Research assistant

Dr. Bryant McAllister
University of Iowa
2002-2005
Investigated climatic factors that contribute to the maintenance of a latitudinally distributed chromosomal polymorphism in clinal populations of \emph{Drosophila americana}. Performed various physiological assays to associate variation in cold tolerance with alternative chromosomal forms.

Research assistant

Dr. Steve Hendrix
University of Iowa
Summer 2005
Participated in a pioneering effort to sample flora and fauna biodiversity in rare hill prairies bordering the Mississippi River in northeastern Iowa. Used GIS to locate hill prairies and scout potential sample sites. Helped to setup plots in the field using laser distance measurement and surveyed insects with sweep-netting.

Teaching experience

Guest Lecturer, Evolution and Biodiversity, Indiana University, Fall 2008

Teaching Assistant, Evolution and Biodiversity, Indiana University, Fall 2008

Guest Lecturer, Principles of Biology: Organisms, Ecology, and Evolution, College of William and Mary, Fall 2007

Teaching Assistant, Principles of Biology: Organisms, Ecology, and Evolution, College of William and Mary, Fall 2007

Teaching Assistant, Introduction to Ecology and Environmental Science, College of William and Mary, Spring 2007

Teaching Assistant, Zoology, College of William and Mary, Fall 2006

Teaching Assistant, Principles of Biology: Molecular Cell and Development, College of William and Mary, Spring 2006

Publications

Folk, D. G., L. A. Hoekstra, and G. W. Gilchrist. 2007. Critical thermal maxima in knockdown-selected Drosophila: are thermal endpoints correlated? J. Exp. Biol. 210, 2649-2656. [PDF]


McAllister, B. F. and L. A. Hoekstra. A latitudinally distributed chromosomal polymorphism affects cold hardiness in Drosophila americana. (in revision)

Publications in prep

Hoekstra, L.A. and Gilchrist, G.W. Metabolic and locomotor performance during acute heat stress
in knockdown-selected Drosophila melanogaster.


Hoekstra, L.A., Moroz, L.L., and Heyland, A. Insights into the structure of the echinoderm nervous
system: abundant histaminergic and FMRFaminergic-like cells in the sea cucumber Leptosynapta
clarki.

Folk, D.G. and L.A. Hoekstra. Wasting breath on a dry death: desiccation resistant Drosophila lack a metabolic response to dessication stress.

Presentations

The significance of energetic constraints on the evolution of inducible physiologies. Poster presentation. Society for Integrative and Comparative Biology Conference. Seattle, WA. January 4th, 2010.

The significance of energetic constraints on the evolution of inducible physiologies. Midwest Drosophila Conference. Allerton, IL. October 3rd, 2009.

The energetic cost of increased thermotolerance in Drosophila melanogaster. Poster presentation. European Society for Evolutionary Biology Conference. Turin, Italy, August 25th, 2009.

The energetic cost of increased knockdown temperature in Drosophila melanogaster. Poster presentation. Drosophila Research Conference. Chicago, IL. March 5th, 2009.

A new perspective on the echinoderm nervous system. Society for Integrative and Comparative
Biology Conference. Boston, MA. January 5th, 2009.


Sexually dimorphic heat shock survival in Drosophila melanogaster. Midwest Drosophila Conference. Allerton, IL. October 4th, 2008.

Hot flies run fast: selection on thermotolerance affects locomotor performance. Society for the Study of Evolutionary Biology Conference. Minneapolis, Minnesota. June 23, 2008.

Energetics of an adaptive heat stress response in Drosophila melanogaster. Poster presentation. European Society for Evolutionary Biology Conference. Uppsala, Sweden, August 21st, 2007. [PDF]

How do organisms adapt to stress? Graduate Research Symposium. College of William and Mary, March, 2007.

Energy spent on a dry death. Function Valued Trait Workshop. National Evolutionary Synthesis Center, North Carolina, January 2007.

Factors influencing the maintenance of a chromosomal cline in Drosophila americana. Poster presentation. Midwest Ecology and Evolution Conference, University of Notre Dame, March 5th, 2004.

Funding

Indiana Metabolomics and Cytomics fellowship, 2010
NSF IGERT fellowship, Indiana University, 2009-2010
Graduate Research Grant, College of William and Mary, $300, Fall 2007
Graduate Research Grant, College of William and Mary, $300, Spring 2007
Graduate Research Grant, College of William and Mary, $300, 2006
Undergraduate Scholarship Assistance Program, University of Iowa, $1250, 2004

Service

Graduate recruiting weekend committe member. Spring 2010.

IGERT symposium organizational committee. Fall 2009.

Graduate recruiting weekend committe member and host. Spring 2009.

Graduate committee for departmental website design. Fall 2008.

Montooth lab webmaster. 2008-2010.

Graduate student representative for Committe on Integrative Response to Climate Change. College of William & Mary, 2007

Graduate search committee for a molecular biologist. College of William & Mary, 2006


Membership in professional societies

Society for the Study of Evolution
European Society for Evolutionary Biology
American Society of Naturalists
Genetics Society of America
Society for Integrative Comparative Biology

References

Dr. Kristi Montooth
Dr. George Gilchrist
Dr. Donna Folk
Dr. Bryant McAllister

   
 

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